Abstract:Objective：To explore the contribution of ultrasonic examination and localization in early breast cancer screening of chinese women with dense breast. Methods：From February, 2002 to April, 2006, the breasts of 5 000 women were examined using ultrasonic examination,and in about 4,000 women a mass was detected, which included 142 cases of breast cancer proved by pathology with diameter ≤2cm occurred in patients with dense breast. In these parients, ultrasonic visualization and molybdenum target mammographic were performed. Results：In these with breast cancer and dense breast,there were 47 cases(33.10％) with microcalcification detected by ultrasonography, the sensitivity rate was 74.60％ and the accuracy rate was 88.73％. Only 38 (26.76％) cases were detected by mammography, the sensitivity rate was 60.32％ and the accuracy was 82.39％.About 44.37％ breast cancer with dense brast display as the microcalcification. There were 110 cases（77.46％） of the small breast cancer detected by ultrasonography, the sensitivity was 88.71％ and the accuracy rate was 90.14％.There were 100 cases（70.42％） detected by mammography, the sensitivity rate was 80.65％ and the accuracy rate was 83.10％. Also, in 12 patients an unpalpation breast lesion was correctly excised by the use of ultrasonic localization.
Conclusions：（1）For the small breast cancer in dense breast the sensitivity and the accuracy of ultrasonography surpassed those of mammography. （2）The ultrasonic examination is an effective way for early breast cancer screening in young women with dense breast and flat breast. Ultrasonography can improve the rate of dignosis in early breast cancer, and also improve the breastconserving surgical rate. Ultrasonography is worth of widespread use spreading.