Abstract:Objective：To study the diagnosis and treatment of the cystic neoplasms of pancreas(CNP). Methods：The clinical data of 30 cases of CNP, with comfirmed by pathology, admitted in our hospital in recent 6 years were retrospective analyzed. Results：CNP was more seen in mid-young women. The course of CNP was longer. Upper abdominal mass and abdminal distention and pain were the main clinical presentations. Ultrasounography, CT and ERCP could be help to the diagnosis of CNP. The CNP resection rate was 80%(in bengin CNP was 100%, in malignant CNP was 70.0%). Of the 7 patients with CNP located at head and neck of pancreas, pancreaticoduodenectomy was performed in 3 patients, near total resection of pancreas pancreas with preserving the duodenum in and small part of the head of pancreas 1, segmental resection of the pancreas in 2, and extraction of the tumor in 1. Among the 17 patients with CNP located at body and tail, resection of the body and tail with or wothout splenectomy in 15 patients, tumor extraction in 1, pancreas segmental resection with Roux-en-y pancreticojejunostomy in 1. The other 6 patients with diffused CNP were unresectable. The main operative complication was pancreatic fistula(20.0%); all the fistula was cured No death occurred in this series. Conclusions：CNP have no clinical characteristics. The discovery of this disease is mainly according to the upper mass and imaging examination(ultrasound , CT etc). The resection rate of CNP is high, the prognosis is good. So that, aggressive surgery treatment must be adopted. Resection of the whole tumor with part paratumor pancreas tissue is advocated.