Abstract:Objective：To explore the methods and the effect of the surgical treatment of patients with chronic ischemia of extremities. Methods：In recent 6 years, the clinical data of 75 patients, including 7 upper extremities and 71 lower extremities with chronic ischemia, treated surgically were reviewed retrospectively. The surgical treatment included: traditional operation in 65 cases, interventional surgery in 4 cases and stem cell transplantation in 6 cases. Results：Sixty-three patients(66 extremities) were followed up from 2 to 56 months after the surgical treatment, and the result showed that 9 extremities of 8 patients were amputated within 1 year（13.6%）. In the other cases（83.3%）, the ischemic symptoms were relieved or disappeared, the ulcer healed or the amputating level had lowered（3.0％）．The effective rate of the surgical treatment was 86.3％.Conclusions：The appropriate surgical treatment of chronic ischemia limbs should be choiced based on the ischemic state of the limb，and a satisfactory result can be obtained in most patients．