Abstract:Objective:To evaluate the surgical therapy for patients with hilar cholangiocarcinoma. Methods:The clinical data, including clinical manifestation, clinical stage, operative approaches and results of the treatments, of 64 patients with hilar cholangiocarcinoma treated during 16 years were retrospectively analyzed. Of the 64 patients, 35cases underwent tumor resection (radical resection in 16cases, palliative resection in 19cases), and 29 patients underwent bile duct drainage operations (internal drainage in 16cases and external drainage in 13cases).
Results:In the radical resection group, the 1-, 2- and 3-year survival rate was 80.0%, 53.3% and 26.7%,respectively; in the palliative resection group, the 1-, 2- and 3-year survival rate was 50.0%, 16.7% and 0%, respectively. In the internal drainage group, the 1- and 2-year survival rate was 45.5% and 18.2%, respectively; in the external drainage group, the 1- and 2-year survival rate was 25.0% and 0%, respectively. Conclusions:Surgical resection, especially radical resection, can improve the therapeutic results and prolong the survival time of patients with hilar cholangiocarcinoma.