Abstract:Objective：To study the effect of reconstructed hepatic blood flow after partial portal vein arterialization on hepatic microvasculature and histology.
Methods ：Experimental model of partial portal vein arterialization was established in rats. The changes of hepatic microvasculature and histology in the rat model were observed.
Results：One month after arterio-portal shunt, the hepatic tissues showed no significant abnormality. However, corrosive cast samples showed that hepatic sinusoids were slightly thicker and their filling was more obvious than normal, but were not obviously deformed, and were distributed around the central vein in a radial form. Ink perfusion samples showed that hepatic sinusoids were regular and slightly wider. Their colour was homogeneous and slightly deeper.
Conclusions：Partial portal vein arterialization has no early effect on hepatic microvasculature and histologic structure.