Abstract:Objective:To detect -174G→C polymorphism of IL-6 gene promoter in patients with colorectal cancer. Methods :-174G→C polymorphism of IL-6 gene promoter was detected by PCR-RFLP in 49 patients with colorectal cancer. Results:-174G→C polymorphism of IL-6 gene promoter in all the 46 patients with colorectal cancer was -174G/G genotype. Conclusions:-174G→C polymorphism of IL-6 gene promoter was not found in 49 patients with colorectal cancer.
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CHEN Jiang-hui, LI Deng-qing, CHEN Zi-hua.Investigation of -174G→C polymorphism of the IL-6 gene promoter in patients with colorectal cancer[J]. Chin J Gen Surg,2007,16(4):12-. DOI:10.7659/j. issn.1005-6947.2007.04.012