Abstract:Objective:To discuss the diagnosis and treatment strategy of cystadenocarcinoma of pancreas.
Methods :The clinical records of 13 cases of cystadenocarcinoma of pancreas were reviewed retrospectively.
Results:Twelve cases showed abdominal pain and distention, and an upper abdominal mass was palpated in 4 cases. The course of disease lasted from one month to five years. On B ultrasound examination, 10 cases showed multiple loculated cystic or cystic solid mass of pancreas, with non-homogeneous echo inside. CT scanning was done in 9 cases, it showed cystic and systic-solid lesion of pancreas and the enhanced image showed cyst wall with partial enhancement, and cyst wall calcified in two cases. Six cases of cystadenocarcinoma were located in the head and neck of pancreas, five in the body and tail, and two involved the whole pancreas. Correct preoperative diagnosis was made in two cases. The excision rate was 69%(10/13) and mortality rate 7.7%（1/13）.All were mucinous cystadenocarcinoma pathologically. One patient died from pancreas fistula. Eight cases were followed up, but four were lost to followup. The survival time was ten months to ten years.
Conclusions:Correct diagnosis of cystadenocarcinoma of pancreas is rather difficult, and the rate of misdiagnosis is high.However, imaging and CA15-3 examination are helpful for diagnosis. With aggressive surgery and combined therapy, a better prognosis can be expected.