The association of intestinal microbiota with hepatobiliary and pancreatic malignancies: a review of research progress
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1.[Zhejiang University of Traditional Chinese Medicine, School of Nursing, Hangzhou 310022, China;2.[Zhejiang University of Traditional Chinese Medicine, Zhejiang Shuren University, Hangzhou, Zhejiang 310053; Shulan (Hangzhou) Hospital, Hangzhou 310022, China;3.[Zhejiang University of Traditional Chinese Medicine, Department of Infectious Diseases, Hangzhou 310022, China;4.[Zhejiang University of Traditional Chinese Medicine, Department of Gastrointestinal and Thyroid Surgery, Hangzhou 310022, China;5.Shulan International Medical College, Zhejiang Shuren University, Hangzhou312028, China;6.Department of Infectious Diseases, Key Laboratory of Artificial Organs and Computational Medicine of Zhejiang Province, Shulan (Hangzhou) Hospital, Shulan International Medical College, Zhejiang Shuren University, Hangzhou310022, China

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R735

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    Abstract:

    The gut microbiota plays a crucial role in maintaining overall health. Dysbiosis of the gut microbiota can promote the occurrence and progression of tumors, especially hepatobiliary and pancreatic tumors, by affecting intestinal homeostasis, gut metabolism, and immune function. Therefore, a better understanding of the role of the gut microbiome in the development and progression of hepatobiliary and pancreatic tumors may provide opportunities for developing new prevention and treatment strategies for patients with these malignancies. This article reviews recent research on the role of gut microbiota in the development and progression of hepatobiliary and pancreatic malignancies, aiming to provide a reference for future studies.

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YANG Hongmei, FENG Zixuan, XU Zixun, WANG Gangyi, WU Huan, FANG Rui, CHEN Ping. The association of intestinal microbiota with hepatobiliary and pancreatic malignancies: a review of research progress[J]. Chin J Gen Surg,2024,33(10):1724-1730.
DOI:10.7659/j. issn.1005-6947.2024.10.019

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History
  • Received:April 12,2024
  • Revised:August 16,2024
  • Adopted:
  • Online: November 18,2024
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