Abstract:The incidence and detection rates of benign and low-grade malignant pancreatic tumors have risen yearly. For patients with such tumors, traditional radical resection procedures often result in excessive loss of normal pancreatic parenchyma, leading to complications such as postoperative insufficiency of both exocrine and endocrine functions. Studies have shown that functional-preserving surgeries, such as minimally invasive enucleation or partial resection surgeries, can maximize the protection of patients' pancreatic function and improve long-term quality of life. However, for some tumors deep within the pancreatic parenchyma, accurately locating the tumor and protecting the pancreatic duct pose challenges. Intraoperative ultrasound (IOUS) has become an ideal intraoperative imaging tool, often referred to as the surgeon's "third eye" because of its portability, ability to provide real-time high-resolution information, non-reliance on ionizing radiation, and the fact that it does not require special patient preparation. With advancements in technology, the application scope of IOUS has expanded beyond its initially limited diagnostic role to various surgical applications, including identifying non-palpable lesions, guiding surgical strategies, and staging tumors. In the current era of minimally invasive and precision surgery, the proficiency of surgeons in using IOUS has become an important issue. This article reviews the history of IOUS applications, summarizes the advantages and basic usage methods of robotic IOUS, and shares techniques for applying IOUS in robot-assisted precise resection of pancreatic tumors.