Objective:To study the operative procedure and effect of anastomostic pseudoaneurysm(APA). Methods:Eleven patients with APA were treated surgically.The diagnosis of APA in all the patients was comfirmed by angiography and ultrasonic examination. A small rupture leading to APA was repaired by lateral arteriorrhaphy using autologous vein patch in 4 cases; the APA caused by a big rupture of anastomosis,resection of the pseudoaneurysm and interposition of a PTFE or antologous vein were used in 7 cases.Results:10cases were followedup for 5-38 months (mean19.6 months),and 1case loss of followup.9 cases recovered to be normal in activities and works, only 1 case had nerve paralysis of the affect extremity caused by popliteal artery APA compression. All the cases have good blood perfusion of the extremities without recurrence. Conclusions: APA should be treated by surgery.During operation control blood vessels effectively and remove the pathological changetissues completely are important,and reasonable application of antibiotics and antithrombotic agents are the guarantee of getting successful results.