Objective:
To evaluate the effect of combination of surgery and transcatheter hepatic arterial chemotherapic embolism(THACE) with or without placement of drug deliery system(DDS) of portal vein for hepatocellular carcinoma with portal vein tumor thrombus (PVTT). Methods:Fifteen cases of advanced HCC with PVTT were treated by hepatectomy， thrombectomy of portal vein with THACE,and 5 of the 15 cases received postoperative chemotherapy via portal vein. Results:All patients survived after operation. The survival rate of 6,12,18 months was 15,12 and 9 cases respectively. Conclusions : Operation is still an effective method for advanced HCC , postoperative comprehensive treatment can improve the survival rate.