Objective:To investigate the feasible and effective means for the lower extremity deep venous thrombosis(DVT).Methods :The clincal data of 211cases of lower extremity DVT treated in recent 9 years were analysed retrospectively.Antegrade infusion of high dose urokinase was performed via the dorsalis pedis vein of the involved lower limb in 179 patients.Of the 179 patients vena cava filters(VCF) was placed in 29 patients,including Tempofilter II VCF in 5patients, VenaTechTM LP VCF in 24patients.Other 32 cases underwent embolectomy after IVC filter placement(Tempofilter II was placed in 6patients, VenaTechTM LP was placed in 26patients). Results: 146 patients were followed up for 3108 months with averge 54months .A total of 61 IVC filters were successfully expanded,but 1 Tempofilter II VCF was migrated to proximal end of IVC.Tempofilter II VCF was taked out 24 week after the IVC filter placement . VenaTechTM LP occlusion in one case 14 months after the IVC filter placement.In thrombolytic group,87were cured,86 improved,6 ineffective. In operative group, 28were cured,3 improved,1 ineffective. The cured rate in operative group was better than that in thrombolytic group(P<0.05),but the total effective rate was similar in both groups.Conclusions: Vena cava filters placement can effectively prevent the formation of pulmonary embolism, but the indication should be strict.Combination of surgery with other therapy is effective in improving the results and preventing the sequela of lower extremity DVT.