ObjectiveTo explore the monitoring methods for pancreatic graft function after upper abdominal cluster transplantation. MethodsAnalysis of the clinical data of 5 cases of successful upper abdominal clustertransplantation in our center. ResultsThe patients recovered well after the operation. Endocrine and exocrine functions of all the pancreas graft returned to normal without any rejection. ConclusionsDynamic monitoring of blood glucose, Cpeptide, blood insulin, blood amylase, urine amylase, amylase in abdominal drainage and duodenal tube decompression drainage, in addition to Doppler color ultrasound examination, can effectively detect the endocrine and exocrine function of the pancreas graft.