Objective:To investigate the effect of short bowel syndrome treated with livingrelated small bowel transplantation(SBT). Methods:A male patient with residual intestine 20cm in length, which resulted from subtotal small bowel resection and right hemicolectomy owing to intestinal volvulus, received a livingrelated SBT. The donor was the patient′s mother. Donor specific blood transfusion,50mL/per week, was carried out for 8 weeks. Cytomegalovirus infection status in both donor and recipient was negative. A 160cm segment of intestine was transplanted. The graft ileocolic artery and vein was anastomosed to the recipient′s infrarenal aorta and inferior vena cava endtoside, respectively. A distal ileostomy was performed. Immunosuppression,antiinfection and anticoagulation therapy, and nutritional support were given postoperatively. Results:The donor had an uneventful recovery. No technical complications were observed. The recipient was alive and well 31 weeks after operation. No graft rejection or infection was found. The patient was taken off TPN 8 weeks after operation, and got a lowfat meal. The result of Dxylose test was near normal. Conclusions:Livingrelated small intestine transplantation is an effective treatment for short bowel syndrome.