乳腺癌保乳手术的治疗及预后
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洪坚善

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Breastconserving therapy for breast cancer and its prognosis
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    目的:探讨乳腺癌保乳手术的方式和预后。方法:回顾性分析笔者所在2所医院10年间保乳治疗69例原发性乳腺癌患者的临床资料,包括保乳术不放疗和保乳术加放疗、化疗和激素治疗。随访12~140个月。结果:保乳手术未放疗组3年复发率11.54%(3/26),显著高于手术加放疗组3.03%(1/33)(P<0.05)。腋窝淋巴结阳性的保乳手术未化疗者,其5年远处转移率(50.0%)高于手术加化疗组(11.1%)(P<0.05)。结论:保乳术后应进行放疗;年轻、淋巴结阳性、组织学分级III级者应辅助化疗。

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    Objective:To explore the effect of breastconserving therapy for breast cancer(BCT) and its prognosis. Methods:The clinical data of 69 cases of BCT admitted from January 1992 to December 2003 were analyzed retrospectively. The cases included those who had BCT without radiotherapy and those who had BCT with adjuvant radiotherapy, chemotherapy and hormonal therapy. The patients were followed up for 12 to 140 months. Results:The 3year recurrence rate for patients without radiotherapy (11.54%) was higher than that for those with radiotherapy (3.03%) (P<0.05). In nodepositive patients, the 5year distant metastasis rate for patients without chemotherapy(49.21%) was higher than that for those with chemotherapy (7.81%) (P<0.05) . Conclusions:Radiotherapy must be given after BCT. Patients who are young or nodepositive, or have histological grade III tumor should receive adjuvant chemotherapy.

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洪坚善,杨建荣,张传珉,刘剑伦,杨南武,陈建思,杨华伟.乳腺癌保乳手术的治疗及预后[J].中国普通外科杂志,2005,14(9):8-.
DOI:10.7659/j. issn.1005-6947.2005.09.008

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  • 在线发布日期: 2005-09-25