Abstract:Objective:To assess the effect of anticoagulant drugs,elastic compression stockings(ECS)and Daflon on the prevetion of the post-thrombotic syndrome (PTS). Methods:Fifty-eight deep venous thrombosis(DVT) patients were divided into control group and treatment group I and II. The control group (n=15) did not take anticoagulant drugs or the time of anticoagulant drug administration was less than 1 month, and the use of (ECS) was less than 3 months. The treatment group I(n=24) took warfarin for 6 months and the ECS were used in the follow-up time; the treatment group II(n=19), besides warfarin therapy and ECS, took Daflon for 12 months. All the patients were followed up, the general conditions were assessed with clinical score, and the therapeatic results of the 3 groups were assessed. Results:The rate of PTS occurrence in control group was significantly higher than that in treatment group 1 and treatment group 2. At 6 months, the clinical score of treatment groups 1 and 2 was significantly lower than that of control group. At 1 and 1.5 years after discharge, the clinical score of treatment group 2 was significantly lower than that of treatment group 1.Conclusions:The long-term comprehensive and systemic therapy (including warfarin, ECS and daflon) for DVT could prevent PTS.