Abstract:Objective:To observe the therapeutic effect of gastric bypass operation on non-obese type 2 diabetes.
Methods :Retrospective analysis the clinical data of 103 non-obese patients with type 2 diabetes underwent gastric bypass operation in our hospital during the last five years, including the body mass index,the fasting blood glucose level,the insulin resistance index,the changes in glycosylated hemoglobin before and after surgery, and the turnover of the diabetes condition six months after surgery.
Results:Postoperatively, comparing to before operation, there was no significant difference in body mass index (P＞0.05); one week after surgery,the fasting blood glucose level showed a sustained and steady downward trend (P＜0.05). With the decrease of the fasting blood glucose,the insulin resistance index and glycosylated hemoglobin also decreased significantly (P＜0.05). Diabetes cure rate was 79.6 percent overall six months later,and there was no significant difference in the control of diabetes between the different types of gastric bypass operation:esophago-jejunum Roux-en-Y surgery and Mo′s gastro-jejunum anastomosis(P＞0.05).
Conclusions:Gastric bypass operation has a good therapeutic effect on type 2 diabetes in the non-obese patients, and this therapeutic effect is not dependent on loss of body weight.