Abstract:Objective:To investigate the effectiveness and limb salvage rate of treatment for occlusion of PTFE grafting in the lower limb. Methods :From July 1998 to May 2007, 86 lower limbs with PTFE grafting occlusion in 79 patients were treated in Xuanwu Hospital. Thrombectomy for PTFE grafting occlusion was performed in 37 limbs (43.1%); thrombectomy combined with new PTFE prosthesis to reconstruction the distant artery was performed in 13 limbs (15.1%); thrombectomy combined with interventional therapy was performed in 13 limbs (15.1%); Re-grafting with new PTFE graft was carried out in 9 limbs (10.5%); medical treatment was used in 7 limbs (8.1%); amputation was performed in 7 limbs (8.1%). Results:Twenty-two limbs in 21 patients were amputated. Eight patients died. The limb salvage rate in revascularization patients was 63%. Conclusions:Thrombectomy in the occluded PTFE graft, thrombectomy combined with graft-tibial or peroneal artery bypass, thrombectomy in PTFE graft combined with interventional therapy, and re-grafting with a new PTFE graft can be used. Those methods are effective treatment and can avoid amputation in most patients.