Abstract:Objective:To summarize the clinical characteristics and the experiences of diagnosis and treatment of splenic tumors.
Methods :A retrospective analysis was performed on the clinical data of 68 cases of splenic tumors confirmed by surgery and pathology.
Results:Benign masses were found in 31 patients(45.59%), including splenic cyst in 15 patients, hemangioma in 12, lymphangioma in 3 and splenic abscess in 1; 37(54.41%) patients with malignant tumors included metastatic tumors of spleen in 24, primary splenic lymphoma in 11, malignant fibrous histiocytoma in 1, and angiosarcoma in 1. The preoperative confirmed diagnostic rate by B-US was 83.82% (57/68) and by CT was 91.18% (62/68). Of the 68 patients, 59 cases underwent splenectomy, 6 cases underwent partial splenectomy, 2 cases of splenic cyst underwent percutaneous drainage and 1 case underwent puncture biopsy. Tweety-two patients with benign tumor were followed up for 7 to 114 months and all are well; 23 of 37 patients with malignant tumor were followed up for 12 to 79 months, of them, 8 lymphoma patients survived 14 to 79 months, and in the other 15 cases, only 3 patients survived more than 2 years and 12 patients died at 3 to 12 months.
Conclusions:B-US and CT are the main methods of diagnosis for splenic tumors, and surgery is the main method of treatment. Benign splenic tumor does not require any other therapy after splenectomy or partial splenectomy. Splenectomy is the treatment of choice for primary malignant splenic tumor. Adjuvant chemotherapy can prolong survival of patients with lymphoma after splenectomy. Metastatic tumors in the spleen require adjuvant treatment after operation.