Abstract:Objective:To investigate the general rule of perioperative hemodynamic changes in liver transplantation patients.
Methods :We retrospectively studied the data of 31 patients who were treated with liver transplantation from July 2007 to December 2007. K value, EHBF, CO, BV and CBV were detected by DDG analyzer on preoperative day and on 1, 3, 7 and 14 postoperative day.
Results:K value, EHBF, CO, BV and CBV detected before operation was （0.09±0.05）/min, （0.43±0.22）L/min, （7.16±2.49）L/min, （5.87±1.85）L, （3.94±1.59）L respectively. Postoperatively, K value and EHBF were significantly higher than that of preoperative day; CO and BV of the 1 postoperative day were significantly higher than that of preoperative day and the 3 and 14 postoperative day; while CBV of the 1 postoperative day was higher than that of other days(P＜0.05).
Conclusions:Before liver transplatation operation the patient has low blood volume and high circulation. In the early postoperative period has high blood volume, high circulatory state, increase of effective hepatic blood flow and rapid recovery of hepatic reserve function. At 3d postoperatively, the high circulatory state markedly decreases, and general circulation gradually enters a stable condition at about 2 weeks after operation.