Abstract:Objective:To investigate early diagnosis and treatment of tumor of duodenal papilla.
Methods :Their clinical data of 64 cases of tumor of duodenal papilla confirmed by operation and pathology were analyzed retrospectively. They included 60 cases of carcinoma of duodenal papilla and 4 cases of adenoma.
Results:The main clinical symptoms were jaundice(42 cases), digestive tract symptoms (35 cases),recurrent cholangitis(7 cases) and hemorrhage of upper digestive tract(1 case). The diagnosis rate accuracy of ERCP,Fiberoptic duodenoendoscopy，MRCP,BUS and CT were 100%,97.3%,82.4%,82.8% and 76.1% respectively.Fifly-five cases underwent pancreatoduodenectomy,5 cases received local resection, and the remaining 4 cases were treated by palliative surgery. The surgical complication rate was 16.1% and the surgical mortality rate was 3.6%. The 1-year,3-year and 5-year survival rate of pancreatoduodenectomy were 67.4%,40.6% and 36.3%.
Conclusions:Jaundice and abdommal pain are the main symptoms of tumor of duodenal papilla.Fiberoptic duodenoendoscopy and ERCP are most effective methods for diagnosis of tumor of duodenal papilla.It is essential to early select radical resection operation so as to improve the results of surgical treatment.