Objective:To investigate the diagnosis and therapy of Crohn′s disease(CD).
Methods:The clinical data of 30 cases of pathologically proven CD from 1992 to 2005 were analyzed, 26 cases were followed up. Results:Among the 30 patients with CD, 13 (43.3%) diagmosed by endoscopy and biopsy. and17 cases（57.7%） were diagnosed by operation and pathology Before operation, 6 cases were diagnosed as acute abdomen,4 cases as ileus,3 cases as massive hemorrhage of gastrointestinal tract,2 cases as colorectal cancer, 1 case as intestinal fistula and 1 case as head mass of pancreas.Of the 26 cases followed up cases,15 cases accepted operation with 5 cases of recurrence; 21 cases have taken drugs,and the total effective rate was 73.1%.
Conclusions:CD is a chronic relapsing disease and is difficult to diagnose.The majority of patients undergo operation due to misdiagnosis or complications.CD is prone to relapse postoperatively, quality of life is poor, and one must heighten awareness of these patients, make early diagnosis,directed therapy, and intensify follow up.