原发性肝癌术后复发的再次治疗
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汤明

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Re-operation for patients with recurrent primary liver cancer
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    摘要:

    目的:探讨原发性肝癌复发后再次手术治疗的可行性及意义。
    方法:选取2003年1月—2008年12月间就治和随访的58例第一次手术后复发的原发性肝癌患者,分为再手术组和消融栓塞组,比较1,3年生存率。
    结果:再手术组23例,均行根治性局部切除加肝动脉化疗泵植入术,术后经肝动脉化疗泵行化疗栓塞。消融栓塞组35例,均行局部射频消融治疗加股动脉穿刺肝动脉插管化疗栓塞。再手术者1,3年生存率分别为100%和82.6%,均显著高于消融栓塞组的82.9%和45.7%。
    结论:原发性肝癌根治性切除术后复发患者,如条件适宜,掌握好手术时机,再次手术治疗是首选方案。

    Abstract:

    Objective:To investigate the feasibility and significance of the re-operation for patients with recurrent primary liver cancer.
    Methods :The clinical data of 58 patients with post-operative recurrence after initial operation for primary liver cancer in our hospital from January 2003 to December 2008 were analyzed. They were divided into re-operation group and the other treatment group, and the 1-and 3-year survival rates were compared.
    Results:The 23 cases of re-operation group were all treated by local radical resection plus hepatic arterial chemotherapy pump implantation, and postoperative chemotherapy was given via hepatic artery chemoembolization pump line.The 35 patients of the other treatment group underwent radiofrequency ablation plus transcatheter hepatic arterial chemoembolization via femoral artery.The 1-and 3-year survival rates in re-operation group was 100% and 82.6% respectively, which was significantly higher than that of the other treatment group (82.9% and 45.7% respectively).
    Conclusions:Re-operation is the treatment of choice for patients with tumor recrrrencr after radical resection of primary liver cancer, provided that the conditions are suitable and the timing of operation is appropriate.

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汤明, 吴飞跃, 罗嘉.原发性肝癌术后复发的再次治疗[J].中国普通外科杂志,2009,18(7):9-.
DOI:10.7659/j. issn.1005-6947.2009.07.009

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  • 在线发布日期: 2009-07-25