Objective
To study the diagnosis and treatment of focal nodular hyperplasia(FNH).
Methods : The clinical data of 28 patients with FNH treated by nonanatomic liver resection in our hospital were retrospectively analyzed.
Results:Among the 28 patients, 20(71.4%) were asymptomatic, 24(85.7%) had normal liver function,and 3(11%) were HBsAg positive.The AFP and CEA levels were normal in all of the patients. On ultrasound, 20（75%）were hypoechoic lesions,and 3（75%）showed a typical hypervascular pattern in the arterial phase and slow wash out in the delay phase on contrast enhanced ultrasound. Multiphasic liver CT and MR imaging demonstrated characteristic features in most patients. All of the patients were treated by nonanatomic liver resection.Twenty-four patients were followed up for 3 months to 6 years.The postoperative outocme was satisfactory and had no recurrence in all the cases,including 4 lesions with dysplasisa on pathologic examination.
Conclusions:FNH has nonspecific clinical manifestations. The imaging findings are of great value in diagnosis,and surgical resection is the optimal treatment for patient with distinct indications of surgery.