Abstract:Objective: To study the relationship of different histological types and degrees of infiltration of gastric adenocarcinoma on lymph node metastasis.
Methods: The clinical data of 1 615 cases of gastric adenocarcinoma were analyzed retrospectively, and the rate and number of lymph node metastasis in different histological types and with different depths of invasion were statistically analyzed.
Results: There were 46 227 lymph nodes collected from 1 615 cases, with an average of 28.62 per case. Lymph node metastasis was found in 1 046(64.77%) cases of gastric cancer and 10 173(22.01%) lymph nodes. Different TNM stages showed different rates of metastasis: T1（M）2.78%, T1（SM）13.61%, T2 55.59%, and T3 84.84% respectively, while the metastatic rate for histolgically welldifferentiated carcinoma was 50.25%, and for lowdifferentiated earcinoma was 78.95%, and both had statistically significant difference(P＜0.001).
Conclusions: Metastasis of gastric adenocarcinoma has close relationship with different histological types,and as the depth of infiltrationis increased, the number and chances of lymph node metastasis are increased.