Objective: To study the clinicopathological features and treatment modality of patients with gastric remnant cancer after distal gastrectomy.
Methods: The data of 25 patients with gastric remnant cancer undergoing surgery during the recent 9 years were analyzed retrospectively.
Results: Patients with gastric remnant cancer showed a greater male predominance(5〖JP20〗∶1). The mean interval between previous gastrectomy and diagnosis of gastric remnant cancer was 24.5 years, ranging from 12 to 35 years.The primary operation was Billroth II reconstruction in 80% of the cases. R0 resection for gastric remnant cancer was performed in 14 cases, Palliative resection in 11 cases, and adjuvant chemotherapy in 18 cases. The 1, 3and 5year overall survival rate was 72.0%, 56.0% and 36.0%, respectively, while the respective survival rate was 78.5%, 71.4%, and 50.0% in radical surgery group, and 63.6%, 36.3% and 18.1% in palliative surgery group（P<0.05）. Overall 5year survival rate of patients in simple surgical therapy group and surgery combined with chemotherapy group was 44.4% and 14.5% (P<0.05), respectively.
Conclusions: An aggressive surgical approach plus chemotherapy is important to achieve better outcomes for patients with gastric remnant cancer.