Objective:To summarize our experience in the diagnosis and treatment of male breast cancer（MBC）.
Methods:A total of 41 patients with MBC treated in our hospital from 1985-2006 were analyzed restrospectively. Forty patients underwent surgery，including radical mastectomy（11 cases），modified radical mastectomy（25 cases），and simple mastectomy（4 cases）.
Results:Clinical TNM stage of the cancer was stage Ⅰ（8cases），stageⅡ（19 cases），stage Ⅲ（11 cases）and stage Ⅳ（3 cases）.The median follow-up period was 7.2 years（range，1-20 years），and the follow-up rate was 95.1%. The total 5-year overall survival was 65.9%. The 5-year survival after radical mastectomy, modified radical mastectomy, and simple mastectomy was 25%, 72%and 72.7% respectively.
Conclusions:The modified radical mastectomy is the surgical method of first choice for MBC. The influential factors on prognosis of MBC include type of operative procedure，the status of axillary lymph node， TNM tumor stage，the pathological type and the ER status.