改良胆道重建技术在肝移植手术中的应用
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朱晓峰E-mail:zxf111@hotmail.com

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广东省科技计划项目(2006B36002001)。


Improved bile duct reconstruction for orthotopic liver transplantation
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    摘要:

    目的:探讨改良胆道重建技术在肝移植手术中应用的可行性。
    方法:回顾分析2年间完成的131例肝移植患者的临床资料。根据胆道重建方式将其分为2组:A组(n=76)为接受传统胆道重建术的患者,B组(n=55)为接受改良胆道重建技术的患者。所有手术为同一组术者实施,手术技术熟练。两组患者在性别、年龄、手术指征及肝功能评分等方面均相似。比较两组患者的胆道吻合时间,与吻合口相关的胆道并发症等。
    结果:胆道吻合A组平均时间为(14±2)min,B组为(13±2)min,两组之间差异无统计学意义(P>0.05)。A组中4例(5.3%)出现吻合口相关的胆道并发症;2例为胆道狭窄,经内窥镜逆行胰胆管造影(ERCP)扩张放置支架后症状缓解,2例为胆瘘,经非手术治疗后痊愈。B组中1例(1.8%)出现与吻合口相关的并发症,经ERCP治疗后痊愈。两组之间差异有统计学意义(P<0.05)。
    结论:改良胆道重建技术是一种较理想的胆道重建方式,简便易行,术后胆道并发症少。

    Abstract:

    Objective: To stud the clinical application of improved bile duct reconstruction in liver transplantation.
    Methods: We retrospectively analyzed the clinical data of 131 patients who received liver transplantation from September 2005 to September 2007. The patients were divided into two groups according to the method of bile duct reconstruction. Group A (n=76) received traditional bile duct reconstruction, group B (n=55) received improved bile duct reconstruction. All operations were done by one operation team. The 2 groups were similar in age, gender, liver transplantation indications and Child-Pugh score. We mainly analyzed the time of bile duct reconstruction and postoperative biliary complication associated with anastomsis.
    Results: We spent 14±2 min to reconstruct the bile duct in the traditional method group, and (13±2) min in the new method group (P<0.05).In A group, 4 cases (5.3%) encountered the biliary complication associated with anastomsis, 2 cases suffered from biliary strictures were cured by ERCP(endoscopic retrograde cholangiopancreatography); two cases suffered from bile leaks were recovered by conservative therapy. In B group, 1 case (1.8%) suffered from biliary complication associated with anastomsis was cured by ERCP.
    Conclusions: The new bile duct reconstruction is easier and has fewer complications. It may be an ideal method for bile duct reconstruction in liver transplantation. 

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杨建安, 朱晓峰, 何晓顺, 马毅, 王国栋, 胡安斌, 邰强.改良胆道重建技术在肝移植手术中的应用[J].中国普通外科杂志,2010,19(1):5-7.
DOI:10.7659/j. issn.1005-6947.2010.01.002

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  • 收稿日期:2009-07-10
  • 最后修改日期:2009-11-03
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  • 在线发布日期: 2010-01-15