Objective: To evaluate the safety and feasibility of laparoscopic cholecystectomy（LC） in patients with cirrhosis, and compare the value of model for end-stage liver disease (MELD) score and Child-Pugh classification in predicting prognosis.
 Methods: We reviewed the records of 55 laparoscopic cholecystectomies in cirrhotic patients in our department in the recent 11 years. Indications included symptomatic gallbladder disease, cholecystitis, cystic polyps and cystic adenoma. MELD score and Child-Pugh class were preoperatively calculated and associated with postoperative results. Data regarding patients and surgical outcome were retrospectively analyzed.
 Results: No perioperative death occurred. Total cholecystectomy was employed in 53 patients and subtotal cholecystectomy in 2 patients. Median operative time was（77±5.1）min. Median intraoperative blood loss was(51.0±3.33)mL. Median hospital stay was（5.0±1.3）days. Postoperative complications occurred in 9.09% of the patients, including hemorrhage, intra-abdominal collections and wound complications, which were all controlled conservatively. The incidence of postoperative complications in Child A patients was 7.27%, in Child B was 10.0%; in MELD score below 14 was 2.44%, and in MELD score above 14 was 28.57%. The difference between rates of postoperative complications in patients with preoperative MELD score above 14 and below 14 was significant(P＜0.05), while that between Child-Pugh A and B was not significant (P＞0.05).
 Conclusions: Laparoscopic cholecystectomy is a safe procedure for selected cirrhotic patients, and with controllable complications. MELD score appears to predict morbidity more accurately than Child-Pugh classification system.