Abstract:Objective:To analyze the clinicopathologic features, effect of surgical treatment and prognosis of elderly patients with gastric cancer.
Methods:The records of 84 elderly patients (aged 80 years or above) with gastric cancer who underwent operation in our hospital from 2000-2008 were analyzed retrospectively.
Results:Ten patients had early gastric cancer (1a,8 cases, 1b, 2cases), stage II 12 cases, stage III 45 cases (53.6%) and stage IV 17 cases. Among them, 81% patients had one or more co-morbidities. Cardiovascular disease was present in 43 cases(51.2%). Resection rate was 85.7% (72/84). Radical resection rate was 60.7%(51/84). Limited nodal dissection(<D2) was done in 27 cases (52.9%). D2 dissection was performed in 20 cases (47.1%).The postoperative complication rate was 28.6%, and the rate of surgical related morbidities was 6.0%. The main non-surgical complication in postoperative period was pulmonary infection (14.3%). The tumor size was an independent risk factor for postoperative complications (P=0.009). Postoperative mortality was 3.6% (n=3).The 5 years survival rate was 63.0% for limited nodal dissection and 50.0% for D2 dissection. Total survival rate for radical resection was 56.9%. The 5-year survival rate for stage I cancer was 80.0%.
Conclusions:Gastrectomy with limited nodal dissection in elderly patients with gastric cancer and mild preoperative co-morbidity is safe and effective, and can achieve a good prognosis.