Abstract:Objective:To appraise the postoperative anti-reflux function of vertical esophagogastic valve-plasty anastomosis for cardiac cancer.
Methods:Forty patients with cardiac cancer were randomly divided into study group and surgery control group, with 20 patients in each group.The study group underwent vertical esopagogastric valve-plasty anastomosis, while the surgery control group underwent conventional esophagogastrostomy. Ten healthy volunteers were recruited as normal control group. A 24-hour esophageal pH monitoring and endoscopy check-up was carried out in all experimental subjects at 90 days postoperatively.
Results:All of the pH monitoring indexes in study and surgery control groups were higher than those in normal control group (P<0.05), and those in surgery control group were higher than those in study group (P<0.05), and the degree of gastro-esophageal reflux and histological mucosal inflammation in study and surgery control groups were higher than those in normal control group (P<0.05), while those in surgery control group were higher than those in study group (P<0.05).
Conclusions:The operative type of vertical esophagogastric valve-plasty anastomosis has some reflux phenomenon, but it has marked antireflux effect compared to the traditional operation.