食管胃垂瓣吻合在贲门癌术后抗反流的临床研究
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刘伟平 E-mail:yangjiwu-001@163.com

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Clinical study on postoperative anti-reflux function of vertical esophagogastic valve-plasty anastomosis for cardiac cancer
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    摘要:

    目的:评价食管胃垂瓣吻合术式在贲门癌术后抗反流的作用。
    方法:将40例贲门癌患者随机分成研究组和手术对照组,每组20例,吻合方式分别采用食管胃垂瓣吻合术和传统食管胃吻合方式。在术后3个月分别采用24 h pH监测及胃镜检查,观察术后胃食管反流情况。另选10例健康人设为正常对照组。
    结果:术后近期研究组及手术对照组pH各项监测指标均高于正常对照组(P<0.05),手术对照组高于研究组(P<0.05);两组反流性食管炎分级及组织学食管黏膜炎症程度均高于正常对照组(P<0.05),而手术对照组高于研究组(P<0.05)。
    结论:食管胃垂瓣吻合术后也有一定的反流现象,但和传统手术相比,食管胃垂瓣吻合术具有明显抗反流作用。

    Abstract:

    Objective:To appraise the postoperative anti-reflux function of vertical esophagogastic valve-plasty anastomosis for cardiac cancer.
    Methods:Forty patients with cardiac cancer were randomly divided into study group and surgery control group, with 20 patients in each group.The study group underwent vertical esopagogastric valve-plasty anastomosis, while the surgery control group underwent conventional esophagogastrostomy. Ten healthy volunteers were recruited as normal control group. A 24-hour esophageal pH monitoring and endoscopy check-up was carried out in all experimental subjects at 90 days postoperatively.
    Results:All of the pH monitoring indexes in study and surgery control groups were higher than those in normal control group (P<0.05), and those in surgery control group were higher than those in study group (P<0.05), and the degree of gastro-esophageal reflux and histological mucosal inflammation in study and surgery control groups were higher than those in normal control group (P<0.05), while those in surgery control group were higher than those in study group (P<0.05).
    Conclusions:The operative type of vertical esophagogastric valve-plasty anastomosis has some reflux phenomenon, but it has marked antireflux effect compared to the traditional operation.

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杨继武|刘伟平|周业庭|姜志良|黎瑞.食管胃垂瓣吻合在贲门癌术后抗反流的临床研究[J].中国普通外科杂志,2010,19(4):392-395.
DOI:10.7659/j. issn.1005-6947.2010.04.015

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  • 收稿日期:2009-07-07
  • 最后修改日期:2009-11-23
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  • 在线发布日期: 2010-04-15