扩大根治性切除治疗胰头癌
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向旭E-mail:xiangxu1969@163.com

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Extended pancreaticoduodenectomy for carcinoma of head of pancreas
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    摘要:

    目的:探讨胰腺癌扩大根治性切除术治疗胰头癌的疗效。
    方法:采用回顾性临床对照研究,将75例实施胰十二指肠切除的胰头癌患者按手术曰期分为对照组(n=38)和研究组(n=37),比较两者的生存率、手术并发症发生率、围手术期死亡及复发率。
    结果:对照组和研究组的手术并发症发生率分别为60.53%和29.73%;3年生存率分别为15.79%和35.14%;3年复发率分别为78.95%和35.14%。差异均有统计学意义(P<0.05)。围手术期病死率分别为5.26%和2.70%(P>0.05)。
    结论:扩大根治性胰十二指肠切除术能降低胰头癌术后复发率,提高3年生存率。

    Abstract:

    Objective:To study the effect of extended Whipple′s resection for carcinoma of head of pancreas.
    Methods:Seventy-five patients who underwent surgery for carcinoma of head of pancreas were divided into control group (traditional Whipple′s operation,n=38) and study group (extended Whipple′s operation, n=37). The survival, complication, mortality and recurrence rates were compared between the 2 groups.
    Results:In control group and study group, the complication rate was 60.53%and 29.73%;  the  mortality rate was 5.26% and 2.70%; the recurrence rate was 78.95% and 35.14%; and 3-year survival rate was 15.79% and 35.14%, respectively.
    Conclusions:Extended Whipple′s resection for carcinoma of head of pancreas can decrease postoperative recurrence rate and  increase 3-year survival rate.

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向旭| 王道石| 邱仁央| 文春花.扩大根治性切除治疗胰头癌[J].中国普通外科杂志,2010,19(5):539-542.
DOI:10.7659/j. issn.1005-6947.2010.05.019

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  • 收稿日期:2009-02-05
  • 最后修改日期:2010-04-17
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  • 在线发布日期: 2010-05-15