Objective:To investigate the clinical features and outcome of liver transplantation for benign end-stage liver disease in recipients over sixty years of age. 
Methods:From June 2002 to January 2008, the clinical data of patients with benign liver disease who underwent liver transplantation in our department were analysed retrospectively. The aged group consisted of patients ≥60 years (n=19) and the adult group consisted of patients aged between 18 years to 59 years (n=88). Preoperative laboratory indexes and complications, variables of intra-operation, postoperative complications and 2-year survival rate were compared between the two groups. 
Results:Preoperative diabetes mellitus and the level of serum creatinine, intensive care unit (ICU) length of stay and postoperative deep fungal infection in the aged group were significantly higher than those in adult group (P＜0.05). There was no statistically significant difference in 2-year survival rate between the two groups (P＞0.05). 
Conclusions:Compared with adult group，aged group has higher incidence of diabetes mellitus, lower renal function reserve preoperatively, and postoperative deep fungal infection. Moreover，with close monitoring of patients in the perioperative period，effective support of vital organs and judicious use of immunosuppressants, the prognosis of elderly patients with benign hepatic disease after liver transplant is comparable to adult recipients.