Objective:To investigate the application of selective hepatopetal blood occlusion techniques  in anatomic hepatectomy.
Methods:We retrospectively reviewed the clinical data of 259 patients with hepatolithiasis or liver tumor undergoing anatomic hepatectomy under selective hepatopetal blood occlusion from January 2006 to December 2009.
Results:Totally, 183 cases with hepatolithiasis and 76 cases with liver tumor underwent anatomic hepatectomy under selective hepatopetal blood occlusion. The average intra-operation blood loss was 210 mL（120-1 600 mL）; post-operation incidence of complications and the rate of residual stones was 10.9% and 4.2%, respectively. Thre was no operative death in this series. The intrahepatic recurrence and metastasis rate of liver tumor was 23.6% and the median recurrence was 16.3 months.
Conclusions:The use of a appropriate selective hepatopetal blood occlusion during anatomic hepatectomy for hepatolithiasis and liver tumors is an effective measure to reduce surgical complications and improve outcome.