原发性肝癌自发性破裂大出血的外科治疗:附46例报告
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贾慧民 E-mail:jack120_2008@sina.com

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Surgical management of spontaneous rupture of hepatocellular carcinoma:a report of 46 cases
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    摘要:

    目的:探讨原发性肝癌自发性破裂(SRHCC)出血的合理治疗方法。
    方法:回顾性分析5年半间手术治疗SRHCC 46例的临床资料。根据不同情况,采用急诊一期切除与二期切除两种手术治疗,观察各手术的并发症、围手术期病死率及远期疗效。
    结果:急诊一期肝癌切除术者(A组)与我院非破裂出血的行择期性手术的肝癌配对患者(B组)比较,前者并发症多,围手术期病死率高;远期疗效无明显差别。二期肝癌切除术者(C组)与我院非破裂出血的行择期性手术的肝癌配对患者(D组)比较,并发症及围手术期病死率相近,远期疗效差。A组与C组比较,A组并发症多,围手术期病死率高,远期疗效优于C组。
    结论:SRHCC治疗方法的选择,仍需强调个体化;在经过临床选择的患者中,急诊一期肝癌切除术治疗SRHCC是安全可行的,疗效显著。

    Abstract:

    Objective:To study the rational  treatment of spontaneous rupture of hepatocellular carcinoma(SRHCC).
    Methods:The clinical data of 46 patients with SRHCC treated by 3 operation strategies during five and a half years were retrospectively analyzed.
    Results:Compared with non-SRHCC matched selective operation group(group B), emergency hepatectomy (group A) had more complications and high mortality,but the long-term survival was not significantly different(P>0.05). Compared with non-SRHCC matched selective operation group (group),second stage hepatectomy (group C)had similar rate of complications and mortality,but the long-term survival was worse(P<0.05). Compared with group C,group A had more complications and higher mortality, but the long-term survival rate was better(P<0.05).
    Conclusions: The patients with SRHCC should be managed individually. Emergency hepatectomy is safe and effect, it can be recommended in selected patients.

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侯本新|贾慧民|王喜艳.原发性肝癌自发性破裂大出血的外科治疗:附46例报告[J].中国普通外科杂志,2010,19(7):793-796.
DOI:10.7659/j. issn.1005-6947.2010.07.018

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  • 收稿日期:2010-01-18
  • 最后修改日期:2010-06-08
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  • 在线发布日期: 2010-07-15