Objective:To explore the efficacy of central pancreatectomy for patients with benign pancreatic lesions.
Methods:The clinical charactesistics, operative methods and therapeutic results of twelve patients with benign pancreatic lesions were retrospectively analyzed.  Seven patents with islet cell tumor and 3 patients with true pancreatic cyst underwent central pancreatectomy, closure of the proximal pancreatic stump and Roux-en-Y anastomosis of the distal segment of pancreas; two patients with pancreatic calculi underwent calculi extraction, central pancreatectomy and Roux-en-Y pancreato-jejunostomy of the proximal and distal pancreatic segments.
Results:There were no deaths, pancreatic fistula or other complications in this series. No abdominal pain, fever or hypoglycemia at 6 montns to 3 years  follow-up period.
Conclusions:Central pancreatectomy is an effective method for treatment of patients with benign central pancreatic lesions.