MELD评分系统评估慢性肝损伤患者肝脏储备功能的临床研究
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张捷 E-mail:huangjietdg@126.com

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Hepatic functional reserve in patients with chronic hepatic injury: Evaluation by MELD scoring system
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    摘要:

    目的:探索MELD 评分评估慢性肝损伤患者肝脏储备功能的价值。
    方法:回顾性分析38例慢性肝损伤性肝脏移植患者术前测定的MELD 评分,同时采用计算机辅助数字图像分析法检测患者肝组织标本的纤维化程度,分析MELD 评分系统与肝组织纤维化图像定量分析的相互关系。
    结果:慢性肝损伤患者的MELD 评分与肝纤维化面积百分比呈直线正相关;Child A,B,C 3组间MELD评分差异也有统计学意义。
    结论:MELD 评分能准确评估慢性肝损伤患者的肝脏储备功能。

    Abstract:

    Objective:To explore the value of MELD scoring system in assessing hepatic functional reserve in patients with chronic hepatic injury.
    Methods:Retrospective analysis of  the preoperative MELD scores of 38 patients with chronic hepatic injury undergoing liver transplantation was made,  the  quantitative values of liver fibrosis by computer-assisted digital image analysis was evaluated after operation, and the correlation between the  MELD score and the percentage of liver fibrosis was analyzed.
    Results:A positive linear correlation was found between MELD score and the percentage of hepatic fibrosis in patients with chronic hepatic injury. In the Child-Pugh A,B and C groups, the MELD score had significant difference(P<0.01).
    Conclusions:MELD scoring system can be used to predict the hepatic functional reserve in patients with chronic hepatic injury.

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黄洁|孙敏|张捷. MELD评分系统评估慢性肝损伤患者肝脏储备功能的临床研究[J].中国普通外科杂志,2011,20(1):75-78.
DOI:10.7659/j. issn.1005-6947.2011.01.018

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  • 收稿日期:2010-08-07
  • 最后修改日期:2010-12-13
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  • 在线发布日期: 2011-01-15