Objective:To study the effect of different medthods of pancreatic duct drainage on prevention of pancreatic fistula after pancreaticoduodenectomy.
Methods:The clinical records of 122 patients who underwent standard pancreaticoduodenectomy were analyzed, retrospectively.  The stented drainage of pancreatic duct was used in 103 of 122patients,  including stented external drainage of pancreatic duct in 36 patients, and stented internal drainage of pancreatic duct in 67 patients; and without stented drainage in 19 patients.
Results:Pancreatic fistula was identified in 21of 103 patients in the drained group (4 in the stented external drainaged group and 17 in the stented internal drainaged group), and in 5 of 19 patients in the nondrained group.The incidence of pancreatic fistula in the drained group (20.4%) had no significant difference compared with the nondrained group (26.3%,P＞0.05), and the incidence of pancreatic fistula in the stented external drained group (11.1%) had no significant differenced compared with the stented internal drained group (25.4%,P＞0.05).
Conclusions:Comparing the incidence of pancreatic fistula from both groups,the authors believe that the stented drainage of pancreatic duct does not significantly reduce the incidence of pancreatic fistula after pancreaticoduodenectomy.