乳腺管状腺癌与浸润性导管癌临床病理特征和预后比较
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赵冀安 E-mail:zhaoji-an-88@163.com

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Comparison of the clinicopathologic features and prognosis between tubular carcinoma and invasive ductal carcinoma of the breast
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    摘要:

    目的:比较乳腺管状腺癌(tubular carcinoma, TC)与浸润性导管癌(invasive ductal carcinoma, IDC)的临床病理特征和预后。 方法:回顾性分析1996—2009年乳腺癌手术治疗分期为I/II的41例TC患者和分期为I/II的2 568例IDC患者的临床资料, 比较两者的临床病理特征和预后。 结果:与IDC相比较, TC更容易用钼靶X线检测出(71% vs. 22.9%, P<0.05), 肿物较小, 很少有淋巴结浸润(8.6% vs. 22.9%, P<0.05)。TC和IDC的复发率分别为7.9%和25.7%(P<0.05), TC的无病生存期显著高于IDC(P<0.05)。 结论:TC有着较好的临床病理特征和预后。此外, TC患者与正常人的预期寿命相似, 所以辅助性化疗可能不适于作为TC的常规治疗。

    Abstract:

    Objective:To compare the clinicopathologic features and prognosis between tubular carcinoma (TC) and invasive ductal carcinoma (IDC) of the breast. Methods:The clinical data of 41 patients with stage I/II TC and 2 568 patients with stage I/II IDC, treated with breast surgery, from 1996 to 2009, were analyzed retrospectively, and the clinicopathologic features and prognosis between the 2 groups were compared. Results:Compared with IDC, TC was more likely to be detected by mammographic screening (71% vs. 22.9%, P<0.05), and had smaller median size and showed less lymph invasion (8.6% vs. 22.9%, P<0.05). The rate of recurrence in TC and IDC was 7.9% and 25.7% (P<0.05), respectively. The disease-free survival of TC was higher than IDC (P<0.05). Conclusions:TC is associated with more favorable clinicopathologic features and outcome. In addition, the life expectancy of patients with TC is similar to that of normal individuals, and as a consequence, adjuvant systemic chemotherapy may not be justified as routine management for TC.

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赵冀安, 陈进军, 丁源一.乳腺管状腺癌与浸润性导管癌临床病理特征和预后比较[J].中国普通外科杂志,2011,20(5):467-470.
DOI:10.7659/j. issn.1005-6947.2011.05.010

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  • 收稿日期:2010-12-09
  • 最后修改日期:2011-04-18
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  • 在线发布日期: 2011-05-15