1148例Budd-Chiari综合征的流行病学分布研究
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庄银苹 E-mail:zyp-xz@163.com

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徐州医学院课题资助项目(2010KJ02)。


Epidemiological investigation of 1148 patients with Budd-Chiari syndrome
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    摘要:

    目的:了解Budd-Chiari综合征(BCS)的临床流行病学特点,为其基础疾病的病因研究提供流行病学依据。
    方法:收集徐州医学院附属医院20年收治的来自全国各地1148例BCS患者的流行病学资料。按发病部位分为肝静脉、下腔静脉和肝静脉并下腔静脉混合发病3种类型8种亚型;对各类型的发病年龄、性别、分布区域进行描述性分析。
    结果:20年来BCS发病呈逐年增多趋势;成人多发,男女比例为1.00∶1.25。下腔静脉型发病率最高,肝静脉型次之,肝静脉并下腔静脉混合型最少。患者以江苏、安徽、山东、河南、湖南居多,其中江苏占50.61%。有7.75%的BCS患者术后发生再狭窄。
    结论:徐州医学院附属医院接治的BCS患者以下腔静脉阻塞型为主,患者多居住于黄河流域附近,病因不明,但可供BCS基础疾病的病因研究提供参考。

    Abstract:

    Objective:To analyze the clinical epidemiological characteristics of Budd-Chiari syndrom (BCS), and provide an epidemiological basis for the etiological study on its underlying diseases.
    Methods:The epidemiological data of 1148 patients with BCS from all area of our country, who treated in the affiliated Hospital, Xuzhou Medical College in the last 20 years, were collected. According to the pathogenic location, BCS was divided into three types [hepatic vein (HV), inferior vena cava (IVC) and HV combined with IVC (MIX)] and eight subtypes. A descriptive analysis was carried out by age, sex and regional distribution.
    Results:The cases of BCS had gradually increased in the last 20 years, especially in adults. The ratio between male and female was 1.00∶1.25. The IVC type accounted for most of the cases,while  HV and MIX types were the second and the least, respectively. The majority of the patients came form the provinces of Jiangsu, Anhui, Shandong, Henan and Hunan. Among them, the patients of Jiangsu accounted for 50.61% of BCS cases. Restenosis developed in about 7.75 percent of patients after interventional treatment.
    Conclusions: IVC is the main type of BCS admitted to the affiliated Hospital, Xuzhou Medical College. Most of the BCS patients live around the Yellow River region, and the cause of the disease is not clear. Our study may provide a reference for etiological study on underlying diseases of BCS.

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庄银苹|祖茂衡|张庆桥.1148例Budd-Chiari综合征的流行病学分布研究[J].中国普通外科杂志,2011,20(6):614-617.
DOI:10.7659/j. issn.1005-6947.2011.06.016

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  • 收稿日期:2011-02-17
  • 最后修改日期:2011-06-08
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  • 在线发布日期: 2011-06-15