Objective：To explore the effect of a modified pancreaticojejunostomy on the incidence of pancreatic fistula after pancreatoduodenectomy.
Methods：The clinical data of 78 patients undergiong pancreaticojejunostomy were retrospectively analyzed. The anastomoses of pancreas and jejunum were performed by a modified pancreaticojejunostomy (modified group) or the conventional pancreaticojejunostomy (conventional group), respectively, and the incidences of pancreatic fistula and clinical outcomes of the two groups after surgery were observed.
Results：Of the 48 patients in the modified group, postoperative complications occurred in 5 cases (10.4%) that included 1 case of pancreatic fistula (2.1%). Of the 30 patients in the conventional group, postoperative complications occurred in 11 cases (36.7%) that included 5 cases of pancreatic fistula (16.7%), and 1 case died of abdominal infection and hemorrhage secondary to the pancreatic fistula. All the 77 cases recovered and were discharged from hospital.
Conclusions：The application of the modified pancreaticojejunostomy in pancreatoduodenectomy can reduce the incidence of pancreatic fistula, and it is an effective procedure for the prevention of the pancreatic fistula after pancreatoduodenectomy.