主动脉夹层的血流动力学数值仿真
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郭伟 E-mail:pla301dm1@vip.sina.com

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Numerical simulation of hemodynamics in aortic dissection
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    摘要:

    目的:建立基于CT的胸主动脉夹层有限元模型并进行血流动力学数值模拟,为分析胸主动脉夹层的血流动力学机理及其临床治疗提供理论依据。
    方法:依据胸主动脉夹层患者CT数据,用MIMICS 13.0数字化影像处理软件,获取胸主动脉夹层的优化表面模型,随后导入ANSYS 11.0进行胸主动脉夹层模型的有限元体网格划分。最后在ANSYS CFX 11.0中完成胸主动脉夹层的血流动力学分析。
    结果:成功建立了临床上适用于胸主动脉夹层患者血流动力学分析的有限元模型。获得了个性化胸主动脉夹层模型中血液流场的流线、速度矢量、血管壁面压力和血管壁面切应力的分布和变化。
    结论:模型具有数字化、个性化特征,可用于胸主动脉夹层血液动力学计算和临床胸主动脉夹层患者的破裂机理的研究。

    Abstract:

    Objective: To construct a CT scan-based finite element model of thoracic aortic dissection and numerically simulate its hemodynamic profiles, so as to provide a theoretical basis for the hemodynamic mechanism study and clinical management of thoracic aortic dissection.
    Methods: Based on the patient-specific CT data of thoracic aortic dissection, the optimized surface model of thoracic aortic dissection was constructed by using the image processing software (MIMICS 13.0), which was then imported into ANSYS 11.0 for finite element mesh dividing. The hemodynamic analysis of thoracic aortic dissection was finally performed by ANSYS CFX 11.0 softeare.
    Results: A finite element model for hemodynamic analysis of patient-specific thoracic aortic dissection was successfully constructed. The distribution and changes of streamlines, velocity vector, pressure and wall shear stress were obtained for the patient-specific model.
    Conclusions: This model has digital and patient-specific features and can be used to analyze the hemodynamics and mechanism of rupture of thoracic aortic dissection.

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杨晓冬|郭伟|王中华|田磊|陈学东|王世华.主动脉夹层的血流动力学数值仿真[J].中国普通外科杂志,2011,20(12):1289-1293.
DOI:10.7659/j. issn.1005-6947.2011.12.001

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  • 收稿日期:2011-08-01
  • 最后修改日期:2011-11-03
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  • 在线发布日期: 2011-12-15