Objective: To investigate the clinical application value of immediate repair using mammary/perimammary tissue displacement technique for local defect after breast-conserving therapy. Methods: The clinical data of 87 breast cancer patients undergoing immediate repair using mammary/perimammary tissue displacement technique during breast-conserving surgery between January 2009 and January 2012 were reviewed. The characteristics and clinical applicability of this technique were analyzed, and the postoperative complications and cosmetic results were assessed. Results: Repair operation was successfully performed in all the 87 patients, of whom, 61 cases underwent mammoplasty with adjacent gland tissue flap, 12 cases underwent mammoplasty with lateral thoracic fascial flap, and 14 cases underwent mammoplasty with partial latissimus dorsi muscle flap. There were no severe postoperative complications in any of the whole group of patients. Postoperative follow-up was 12 to 27 months and no local recurrence occurred. The cosmetic results were excellent or good in 75 (86.1%) cases, and fair in12 (13.7%) cases. The reconstructed breasts showed natural and symmetrical appearance with good hand-feeling. Conclusion: Application of immediate repair using mammary/perimammary tissue displacement technique for local defect during breast-conserving therapy can avoid serious breast deformation and maintain the dense breast appearance. This procedure is easy, safe and effective, and is of considerable clinical value.