Short- and medium-term outcomes of laparoscopic radical resection for rectal cancer after neoadjuvant therapy
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摘要:
目的：探讨中低位直肠癌患者在新辅助治疗后行腹腔镜手术的安全性、可行性。 方法：回顾性分析41例新辅助治疗后行腹腔镜手术的中低位直肠癌患者（观察组）与同期48例单纯腹腔镜手术（对照组）中低位直肠癌患者的临床资料。比较两组患者的手术相关指标、术后恢复情况及术后并发症发生率。 结果：两组患者术前条件具有可比性，两组均无手术相关死亡患者。观察组淋巴结清除数明显低于对照组（8.3 vs. 15.2，P<0.01），其余手术相关指标、术后恢复情况以及术后并发症发生率两组间差异均无统计学意义（均P>0.05）。 结论：腹腔镜直肠癌根治术在行新辅助治疗后的中低位直肠癌患者中应用是安全、可行的。
Abstract:
Objective: To investigate the safety and feasibility of laparoscopic radical resection of mid/low rectal cancer after neoadjuvant therapy. Methods: The clinical data of 41 patients with mid/low rectal cancer undergoing laparoscopic radical resection after neoadjuvant therapy (observational group) along with 48 patients with the same condition receiving laparoscopic resection alone (control group) during the same period were retrospectively analyzed. The surgical parameters, postoperative recovery and incidence of postoperative complications between the two groups were compared. Results: The preoperative conditions between the two groups were comparable, and no surgery-related death occurred in either group. The number of resected lymph nodes in observational group was significantly lower than that in control group (8.3 vs. 15.2, P<0.01), while the differences in other surgical parameters and postoperative recovery variables as well as the incidence of postoperative complications between the two groups showed no statistical significance (all P>0.05). Conclusion: Laparoscopic radical resection is safe and feasible in patients with mid/low rectal cancer after neoadjuvant therapy.