Abstract:Objective:To explore the diagnosis, treatment and prognosis of male breast cancer.
Methods :The clinical data of 17 male patients with breast cancer were analyzed retrospectively.
Results:The average age of these 17 patients was 59.6 years. In these 17 male cases, the breast cancer in 3 cases was stageⅠ, in 5 cases stageⅡ,in 7 cases stage Ⅲ, and in 2 cases stage Ⅳ. The major pathological type was typical invasive ductal carcinoma. The breast cancer positive rates of estrogen receptor was 82.4 % and progestogen receptor (PR) was 72.5 %. All of these cases were treated by radical operation and postoperative adjuvant radiotherapy, endocrine therapy and (or) chemotherapy. One patient was lost to follow-up, 2 died of non-tumor disease 8 months and 3 years after operation, respectively, and the other 14 have survived for 1-12 years after operation.
Conclusions:Male breast cancer is an uncommon disease, age of onset is more advanced, and the misdiagnostic rate is high. Tamoxifen is the first choice of hormone therapy. Many factors influence the prognosis of male breast cancer, the most important of which are the TNM stage of tumor, and condition of lymph node involvement.