Background and Aims The unibody single-branched stent graft with the delivery system is a new stent system, which is suitable for aortic dissection with inadequate proximal landing zone, and is a new choice for aortic dissection involving the left subclavian artery (LSA). Here, the authors evaluate the short-term efficacy and safety by summarizing the cases with acute Stanford B aortic dissection and insufficient proximal landing zone undergoing thoracic endovascular aortic repair (TEVAR) with unibody single-branched stent graft.Methods The clinical data of 8 patients with acute Standford B aortic dissection and insufficient landing zone undergoing TEVAR using the Castor^? branched aortic stent graft in Fuwai Yunnan Cardiovascular Hospital from April 2019 to January 2020 were retrospectively collected. The surgical procedures and perioperative complications were analyzed.Results The 8 patients included 7 male cases (87.5%) and 1 female case (12.5%), with a median age of 42 (33-64) years, and BMI of (25.5±3.8) kg/m². The stenting procedure was successfully completed in all patients, the initial technical success rate was 100%, no perioperative death or neurological complications occurred and type I endoleak was noted. The average length of hospital stay was (14.8±3.7) d. The follow-up was performed for 223(60-370) d, and all the main body and branch stent grafts were patent, no associated type I and III endoleak occurred, and no neurological complications and symptoms of left upper limb ischemia were observed.Conclusion The unibody single-branched stent graft combined TEVAR technique is a safe and effect approach for type B aortic dissection with inadequate landing zone. The mid-and long-term results still need further follow-up.