Abstract:Primary hepatic carcinoma refers mainly to hepatocellular carcinoma and intrahepatic cholangiocarcinoma which always lacks standardized diagnostic criteria and system. “Guidelines for the diagnosis of primary hepatocellular carcinoma (2015)” gives the pathologists and clinicians guiding suggestions and advice for the pathologic diagnosis of hepatocellular carcinoma from the respects of gross specimen examination, evaluation of chronic liver disease, small hepatocellular carcinoma, satellite nodules as well as immunohistochemistry which are of deep clinical concern.