With the development of technologies in recent years, endovascular intervention has increasingly matured and gradually taken the place of traditional surgery as a main treatment modality for lower limb arteriosclerosis obliterans (ASO). The efficacy of endovascular intervention in treatment of lower limb ASO is demonstrable, and the technological innovations make its superiority more and more strengthened. Here, the authors, after a comprehensive relevant literature review, extract the achievements from the related clinical trials, and discuss its development prospects.