Acute deep vein thrombosis (DVT) is a clinically frequently-occurring disease. It still has high risk of sudden death, unfavorable short-term results, and high incidence of long-term complications and recurrence, due to the regional differences in medical services and imbalances in economic development, especially the outdated diagnostic concepts. Preventive screening programs for high-risk population of venous thromboembolism (VTE) are urgently required to be carried out at the medical centers of all levels, even the community centers for disease control and prevention. Enhancing the physical and medical preventive measures and increasing the early diagnosis of the latent DVT are essential approaches for preventing lethal pulmonary embolism. According to the subjective and objective needs of the stage of disease, performing a timely “thrombotic clearance” by means of advanced medical equipment is the effective way to reduce long-term complications. Opportune elimination of the anatomic and pathologic causes for DVT recurrence is surely necessary. Strict management during treatment and comprehensive interventions may improve the quality of life for the patients as much as possible.