Objective: To compare the clinical efficacy of laparoscopic right hemihepatectomy (LRH) and open right hemihepatectomy (ORH) in treatment of liver tumor.
Methods: The controlled studies comparing LRH and ORH in treatment of liver tumor published in English and Chinese were searched through online databases. The retrieval time was up to April 2018. After the quality evaluation and data extraction of the included studies, Meta-analysis was conducted by using RevMan5.3 software.
Results: Seven studies were finally included involving 472 patients, with 207 cases in LRH group and 265 in ORH group. The results of Meta-analysis showed that in LRH group compared with ORH group, the intraoperative blood loss was reduced (WMD=–166.14, 95% CI=–254.59––77.68, P<0.000 2), incidence of complications was decreased (OR=0.35, 95% CI=0.21–0.57, P<0.000 1) and length of postoperative hospital stay was shortened (WMD=–4.97, 95% CI=-6.13––3.81, P<0.000 01), while the operative time was prolonged (WMD=51.39, 95% CI=14.88–87.90, P=0.006); no significant differences were noted with regard to the transfusion rate, mortality, surgical margin and tumor size (all P>0.05).
Conclusion: LRH shows no difference in efficacy for the treatment of liver tumor compared with ORH, and also has better safety. However, this conclusion still needs to be verified by more high-quality studies.